The emblem of Vikrama Simhapuri University carries on its top the Sudarsana Chakra indicating the immortality of the pursuit of dispelling the forces of darkness leading to the dawning of the light of truth and wisdom, Tamasoma Jyotirgamaya. The Sudarsana Chakra also shows how Vikrama Simhapuri University carves itself out of the territorial jurisdiction of Sri Venkateswara University, Tirupati. At the bottom of the emblem is the Purna Kumbha, the edifice on which the emblem is poised, signifying a sense of fulfillment, a totality of being that follows true education. In the middle is the Asoka Chakra, symbolizing the quest for dharma that is inclusive. It obliterates distinctions and lays the foundations of equality, and thus access, both of which form the bedrock of the spread of education in tune with the lofty idealism of a democratic society. Nellore, once "Dhanyapuri" or "Nel-ur", is known for its agriculture and hence the vistas of the paddy field in the emblem. Then there is the "V" sign standing for Vikrama Simhapuri University, set against the backdrop of the refulgent glow of the rising sun signifying the new order sought to be ushered in by the establishment of a University in Sri Potti Sri Ramulu Nellore district. Against this horizon of change betokened by the emblem, there is the image of Chandrayan launched by SHAR circling the "V" sign and zooming into the skies, into the infinite space of the universe and into the exploration and discovery of knowledge. The circling of Chandrayan reveals the intertwining of objectives and quests between the University and the world of rapid technological advance. It points in the direction of the spirit of collaborations and common pursuits in search of true unravelling. Chandrayan also represents the transition from an agricultural phase to the technological realm, which Nellore has witnessed in the recent decades on account of the thrust on industrialization and the rapid concourse of trade and commerce consequent on the development of the Krishnapatnam Port.

The Sanskrit epithet for the motto "Satyam Gnanamanantham" is taken from the "Anandavalli" of Taittiriya Upanishad (2.1.1). This sruti vachana proclaims that truth, knowledge and wisdom are infinite and eternal.